Research

Mixed

Continuous positive airway pressure (CPAP) therapy significantly improves subjective and objective daytime sleepiness and self-assessed health status in patients with minimally symptomatic obstructive sleep apnoea (OSA), but does not reduce calculated 5-year vascular risk.

If you have minimally symptomatic OSA, CPAP can still significantly reduce your daytime sleepiness and improve how you feel daily, even if your breathing interruptions aren't severe. However, do not expect this treatment to lower your long-term heart disease risk or blood pressure. The benefit is strictly symptomatic. You should trial CPAP to see if the improvement in alertness and health status justifies the nightly inconvenience, but manage expectations regarding cardiovascular protection.

WeakQualifiesHIGH confidence
CPAP significantly improved subjective daytime sleepiness... objectively measured sleepiness and self-assessed health status. CPAP did not improve the 5-year calculated vascular risk or any of its components.
Sonya Elizabeth Craig et al. · Thorax · 2012

Why this rating

Randomized controlled trial (RCT) with 391 participants, multicentre design, and pre-defined endpoints.

Source

Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial

Sonya Elizabeth Craig et al. · Thorax · 2012

DOI 10.1136/thoraxjnl-2012-202178

rct · n=391Cited 229×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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