Hormonal
Patients with Metabolic Syndrome exhibit higher antioxidant enzyme activities (Catalase, Glutathione Reductase) and protein levels in Peripheral Blood Mononuclear Cells (PBMCs) compared to those without MetS, likely due to a pre-activated state of immune cells.
Your immune cells are working overtime to fight the oxidative stress caused by metabolic syndrome. This is why your body might have higher levels of certain protective enzymes in your white blood cells. It's a sign of your body trying to protect itself, but it also indicates that your immune system is chronically activated, which is a risk factor for long-term health issues.
Higher activities and protein levels of catalase and glutathione reductase in PBMCs were observed in MetS subjects in both genders.
Why this rating
Observational study with clear biochemical measurements and statistical significance.
Source
Metabolic Syndrome Is Associated with Oxidative Stress and Proinflammatory State
Margalida Monserrat-Mesquida et al. · Antioxidants · 2020
DOI 10.3390/antiox9030236
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