Research
Mixed
Gut microbiota composition may influence individual responsiveness to vitamin D supplementation, with non-responders showing specific depletion of Bacteroides acidifaciens.
If you take vitamin D and your levels don't rise, your gut bacteria might be the reason. Specifically, low levels of Bacteroides acidifaciens might predict poor response. This is an emerging area of research.
ModerateQualifiesMEDIUM confidence
We hypothesized that the composition of the gut microbiota might also affect responsiveness to vitamin D intake... Significant decrease in Bacteroides acidifaciens in non-responders.
Why this rating
Observational finding within a trial; hypothesis-generating rather than definitive proof of causality.
Source
The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals
Parul Singh et al. · Scientific Reports · 2020
DOI 10.1038/s41598-020-77806-4
rct · n=80Cited 227×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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