Research
Hormonal
Disruptions to circadian rhythms, specifically changes in habitual bedtime (earlier or later) and awakening time, are significant risk factors for poor sleep quality during lockdown.
Maintain consistent bedtimes and wake times, even when working from home. The data shows that shifting your sleep schedule (either earlier or later) significantly increases the risk of poor sleep. Regularity is more important than total hours when it comes to sleep quality.
GoodSupportsHIGH confidence
Significant factors were found in ... earlier (OR: 1.59; 95% CI: 1.22–2.07) or postponed (OR: 2.10; 95% CI: 1.81–2.41) habitual bedtime, earlier habitual awakening time (OR: 1.47; 95% CI: 1.14–1.90)...
Why this rating
Large sample, multivariate analysis, consistent with existing literature on social jetlag.
Source
Poor Sleep Quality and Its Consequences on Mental Health During the COVID-19 Lockdown in Italy
Christian Franceschini et al. · Frontiers in Psychology · 2020
DOI 10.3389/fpsyg.2020.574475
cross_sectional · n=6439Cited 220×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →