Mixed
Roux-en-Y gastric bypass (RYGB) provides superior long-term type 2 diabetes (T2DM) remission, lower relapse rates, and better glycemic control compared to sleeve gastrectomy (SG) in real-world clinical settings.
If you have Type 2 Diabetes and are considering bariatric surgery, Roux-en-Y Gastric Bypass (RYGB) is associated with better long-term diabetes remission and lower relapse rates compared to Sleeve Gastrectomy (SG). While SG is a common procedure, RYGB may offer superior metabolic benefits for diabetes management, though it involves a more complex surgery. Discuss these long-term outcomes with your surgeon to make an informed choice.
In this large multicenter study, patients who had RYGB had greater weight loss, a slightly higher T2DM remission rate, less T2DM relapse, and better long-term glycemic control compared with those who had SG.
Why this rating
Large multicenter cohort study (n=9710) with long-term follow-up (up to 5 years) and rigorous statistical adjustment, though observational design limits causal inference compared to RCTs.
Source
Comparing the 5-Year Diabetes Outcomes of Sleeve Gastrectomy and Gastric Bypass
Kathleen M. McTigue et al. · JAMA Surgery · 2020
DOI 10.1001/jamasurg.2020.0087
More from this paper
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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