Research
Micronutrients & recovery
High intake of n-3 polyunsaturated fatty acids (PUFA) significantly reduces CVD risk, while the efficacy of n-6 PUFA and combined n-3/n-6 PUFA is inconsistent.
Ensure adequate intake of n-3 PUFA, which has been shown to significantly reduce CVD risk in randomized trials. Be aware that the benefits of n-6 PUFA and combined n-3/n-6 supplements are less clear. Prioritize natural sources of n-3 fats.
GoodQualifiesMEDIUM confidence
two SRMAs of RCTs found that high intake of n-3 polyunsaturated fatty acid (PUFA) significantly reduced CVD risks, with pooled RRs ranging from 0.89 (95%CI: 0.82, 0.98) to 0.90 (95%CI: 0.85–0.96), while evidence of efficacy of n-6 PUFA and combined n-3 and n-6 PUFA were inconsistent.
Why this rating
Based on SRMAs of RCTs, which are high-quality evidence.
Source
Dietary Factors and Risks of Cardiovascular Diseases: An Umbrella Review
Kridsada Chareonrungrueangchai et al. · Nutrients · 2020
DOI 10.3390/nu12041088
Meta-analysis · 54 studiesCited 152×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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