Research
Hormonal
Waist-to-hip ratio (WHR) is a strong predictor of NAFLD risk, with a pooled odds ratio of 4.06 for high vs. low categories.
A high waist-to-hip ratio indicates a higher risk of fatty liver. This metric captures fat distribution, which is crucial for liver health.
ModerateSupportsMEDIUM confidence
The summary OR value was 4.061 (95%CI: 1.529-10.790), with moderate heterogeneity among studies (I2 = 65.7%; P = 0.054).
Why this rating
Based on only 3 studies, leading to moderate heterogeneity.
Source
Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index
Qing Pang · World Journal of Gastroenterology · 2015
DOI 10.3748/wjg.v21.i5.1650
Meta-analysis · 20 studiesCited 211×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Central obesity, measured by waist circumference (WC) or waist-to-hip ratio (WHR), is independently associated with an increased risk of nonalcoholic fatty liver disease (NAFLD), even after adjusting for general obesity (BMI).Good
- General obesity, measured by BMI, is independently associated with an increased risk of NAFLD, even after adjusting for central obesity (WC).Good
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