Research
Hormonal
General obesity, measured by BMI, is independently associated with an increased risk of NAFLD, even after adjusting for central obesity (WC).
Higher BMI is associated with a higher risk of fatty liver, even if you don't have a large waist. Maintaining a healthy weight is important for liver health.
GoodSupportsMEDIUM confidence
A per-unit increase in BMI was independently associated with the risk of NAFLD, with significant heterogeneity among studies (OR = 1.250, 95%CI: 1.131-1.382, I2 = 88.7%; P = 0.000).
Why this rating
Based on 16 studies, but with high heterogeneity (I2 = 88.7%).
Source
Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index
Qing Pang · World Journal of Gastroenterology · 2015
DOI 10.3748/wjg.v21.i5.1650
Meta-analysis · 20 studiesCited 211×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Central obesity, measured by waist circumference (WC) or waist-to-hip ratio (WHR), is independently associated with an increased risk of nonalcoholic fatty liver disease (NAFLD), even after adjusting for general obesity (BMI).Good
- Waist-to-hip ratio (WHR) is a strong predictor of NAFLD risk, with a pooled odds ratio of 4.06 for high vs. low categories.Moderate
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