Micronutrients & recovery

Immune-modulating nutrition (supplementation with glutamine, arginine, omega-3 fatty acids, and antioxidants) does not improve outcomes in general critically ill patients and may increase mortality, although it may benefit specific subgroups like severe burn patients.

Do not routinely use immune-modulating supplements (glutamine, arginine, omega-3s) for general critically ill patients. These supplements have been shown to increase mortality or provide no benefit in large trials. They may be considered for specific subgroups like severe burn patients, but this requires specialist judgment.