Macro partitioning
Administration of specific probiotics, such as Lactobacillus johnsonii N6.2, can hinder the development of diabetes in susceptible models by regulating gut integrity and modulating tight junction proteins like claudin-1.
If you have a genetic predisposition to diabetes or gut issues, maintaining gut barrier integrity is crucial. While this paper highlights Lactobacillus johnsonii N6.2 as a potential helper in animal models, it emphasizes that personalized nutrition and microbiome manipulation are key. Focus on a diet that supports your specific microbiome rather than relying on a single supplement.
a study employing the BB-DP rat model suggested that administration of Lactobacillus johnsonii N6.2 hindered diabetes development through regulation of gut integrity, specifically by modulating the tight junction protein claudin-1 (73).
Why this rating
Based on animal models (BB-DP rats) and cited human studies on microbiota shifts, but specific clinical trial data for this exact strain is not detailed in the text.
Source
Gut Microbiota, Host Organism, and Diet Trialogue in Diabetes and Obesity
Veronica Lazăr et al. · Frontiers in Nutrition · 2019
DOI 10.3389/fnut.2019.00021
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