Research
Mixed
Accelerated metabolomic aging (mAA) is significantly associated with overweight/obesity, heavy alcohol use, diabetes, and depression, indicating that metabolic dysregulation accelerates biological aging markers.
Your biological age, as measured by metabolic markers, speeds up if you have obesity, diabetes, or drink heavily. This isn't just about looking older; it's about physiological decline. Managing weight, limiting alcohol, and controlling blood sugar are direct interventions to slow this specific type of biological aging.
GoodSupportsHIGH confidence
Increased metabolomic age acceleration (mAA) was associated after false discovery rate (FDR) correction with overweight/obesity, diabetes, heavy alcohol use and depression.
Why this rating
Large cohort (N=2,239), multi-platform metabolomics, FDR correction, and validation in an independent cohort.
Source
Determinants of accelerated metabolomic and epigenetic aging in a UK cohort
Oliver Robinson et al. · Aging Cell · 2020
DOI 10.1111/acel.13149
cohort · n=2238Cited 192×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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