Research
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Caloric restriction and specific phytochemicals (e.g., resveratrol, tea catechins) can extend healthspan and modulate aging-related epigenetic marks.
Consider incorporating caloric restriction or consuming phytochemical-rich foods (like those found in tea and grapes) to potentially slow age-related epigenetic changes and support longevity.
ModerateSupportsMEDIUM confidence
For example, age-related increase in levels of 5-hmC in the brain can be prevented by caloric restriction or upregulation of specific endogenous anti-oxidants.
Why this rating
Cited from various studies in the review.
Source
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
Katarzyna Szarc vel Szic et al. · Clinical Epigenetics · 2015
DOI 10.1186/s13148-015-0068-2
narrative_reviewCited 188×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Dietary phytochemicals and macro/micronutrients modulate epigenetic mechanisms (DNA methylation, histone modification) to attenuate 'inflammaging' and promote healthy aging.Moderate
- Specific dietary components (e.g., folate, choline, vitamin B12) influence DNA methylation patterns by affecting the availability of methyl donors like S-adenosylmethionine (SAM).Moderate
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