Research

Energy balance

Obesity is associated with a specific gut microbiota composition characterized by a higher Firmicutes-to-Bacteroidetes ratio, lower bacterial gene richness, and increased gut permeability leading to metabolic endotoxemia.

Obesity is linked to a less diverse gut microbiome with specific bacterial imbalances. While you cannot directly 'buy' a healthy microbiome, eating a diverse, fiber-rich diet supports the bacteria that help regulate energy and inflammation.

GoodSupportsHIGH confidence
Obese individuals tend to have higher proportion of Firmicutes and decreased proportion of Bacteroidetes [45]. ... low gene richness or counts (LGC) correlated with increased trunk-fat and obesity.
Kiran Mazloom et al. · Nutrients · 2019

Why this rating

Consistent observational data across multiple studies, though causality in humans is still debated.

Source

Probiotics: How Effective Are They in the Fight against Obesity?

Kiran Mazloom et al. · Nutrients · 2019

DOI 10.3390/nu11020258

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DOI resolved against Crossref · corpus check 2026-06-10

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