Micronutrients & recovery
Vitamin D3 supplementation (2500 IU/day) does not improve cardiovascular risk markers (endothelial function, arterial stiffness, or inflammation) in post-menopausal women, regardless of baseline vitamin D status.
If you are a post-menopausal woman taking Vitamin D for heart health, this study suggests it likely won't improve your artery stiffness or blood vessel function, even if it successfully raises your blood Vitamin D levels. Continue taking it if recommended for bone health, but do not rely on it as a strategy to prevent cardiovascular disease.
In conclusion, VitD supplementation did not improve endothelial function, arterial stiffness, or inflammation. These observations do not support use of VitD supplementation to reduce cardiovascular disease risk.
Why this rating
Randomized, double-blind, placebo-controlled trial with adequate power, though limited to surrogate endpoints in a specific demographic.
Source
A Prospective Randomized Controlled Trial of the Effects of Vitamin D Supplementation on Cardiovascular Disease Risk
Adam D. Gepner et al. · PLoS ONE · 2012
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