Hormonal
Continuous positive airway pressure (CPAP) therapy reverses oxidative stress and improves endothelial function in patients with obstructive sleep apnea (OSA).
If you have OSA, using CPAP therapy nightly is the most effective way to protect your heart and blood vessels by reversing the oxidative stress caused by breathing pauses. While it can be uncomfortable at first, it is superior to antioxidant supplements for treating the root cause.
Continuous positive airway pressure therapy reverses oxidative stress in OSA. ... most changes in biomarker studies were rapidly reversible after only some nights of CPAP ... CPAP therapy decreases the release of superoxide from leukocytes and increases circulating levels of nitrite and nitrate.
Why this rating
The paper reviews multiple human studies showing reversible biomarker changes, though it notes methodological flaws like lack of sham controls in some.
Source
Obstructive Sleep Apnea, Oxidative Stress, and Cardiovascular Disease: Evidence from Human Studies
Hans-Joachim Eisele et al. · Oxidative Medicine and Cellular Longevity · 2015
DOI 10.1155/2015/608438
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