Hormonal
Increasing viral load (specifically a >= 0.5-log increase) and higher trunk-to-limb fat ratio are significant independent predictors of metabolic syndrome incidence in HIV-infected adults, regardless of BMI adjustments.
Your metabolic health is closely tied to how well your HIV is controlled and where your body stores fat. Keeping your viral load low and monitoring your body composition (specifically trunk fat) are critical. If you notice changes in your body shape or your viral load rises, talk to your doctor about adjusting your treatment or managing your lipids.
The risk was 80% higher among those with at least a 0.5-log increase in viral load in the previous 6 months... the risk increased from 2.3-fold to 4.9-fold with increasing quartile of trunk fat relative to limb fat.
Why this rating
Longitudinal data with robust statistical adjustment for confounders.
Source
Incidence of Metabolic Syndrome in a Cohort of HIV-Infected Adults and Prevalence Relative to the US Population (National Health and Nutrition Examination Survey)
Denise L. Jacobson et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 2006
DOI 10.1097/01.qai.0000243093.34652.41
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