Research

Micronutrients & recovery

Supplementation with Vitamin B complex (B6, B9, B12) reduces homocysteine levels, but this reduction does not necessarily translate to slower cognitive impairment or reduced dementia incidence in the general population.

Ensure adequate intake of Vitamin B6, B9 (Folic Acid), and B12, especially if you have high homocysteine levels, as deficiency is linked to vascular risks. However, do not rely on B-vitamin supplements alone to prevent dementia, as clinical trials show they do not consistently improve cognitive function or reduce dementia incidence in the general population.

ModerateQualifiesMEDIUM confidence
Randomized controlled trials have shown that supplementation with vitamins B can reduce homocysteine levels, although this is not translated into slower cognitive impairment, the improvement of cognitive function, or the reduction of the incidence of dementia.
María Elena Gómez-Gómez et al. · International Journal of Molecular Sciences · 2019

Why this rating

Supported by RCTs showing biomarker reduction but lack of clinical cognitive benefit, suggesting limited utility for general prevention.

Source

Frailty, Cognitive Decline, Neurodegenerative Diseases and Nutrition Interventions

María Elena Gómez-Gómez et al. · International Journal of Molecular Sciences · 2019

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