Research

Mixed

Sleep disturbances are associated with higher all-cause mortality in men, particularly those under 45 years of age, whereas no such association is observed in women.

If you are a man under 45, persistent sleep problems (trouble falling asleep, waking up, or needing medication) are a significant warning sign for premature death. You should prioritize fixing your sleep hygiene and consult a doctor, as this risk is not present in women of the same age group.

GoodQualifiesHIGH confidence
Sleep disturbances were associated with a higher overall mortality risk in men (P = 0.005) but not in women (P = 0.33). This effect was most pronounced for men <45 years of age ((cid:1)3 symptoms vs. none: hazard ratio = 2.03, 95% confidence interval: 1.24, 3.33).
Naja Hulvej Rod et al. · American Journal of Epidemiology · 2010

Why this rating

Large prospective cohort (n=16,989), long follow-up (19 years), low loss to follow-up, validated sleep measures, adjusted for confounders.

Source

Sleep Disturbances and Cause-Specific Mortality: Results From the GAZEL Cohort Study

Naja Hulvej Rod et al. · American Journal of Epidemiology · 2010

DOI 10.1093/aje/kwq371

cohort · n=16989Cited 177×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →