Micronutrients & recovery
Micronutrient deficiencies are widespread in HIV infection and are associated with accelerated disease progression, increased mortality, and higher mother-to-child transmission rates, though supplementation outcomes vary.
Micronutrient deficiencies are common in HIV and can worsen outcomes. While general multivitamin supplementation is often recommended, high-dose single-nutrient supplements can be harmful or ineffective. Focus on a balanced diet and follow WHO guidelines for micronutrient intake, which recommend ensuring 1 Recommended Nutrient Intake (RNI) of each required micronutrient.
Deficiencies of several micronutrients have been associated with accelerated disease progression, increased mother-to-child transmission, increased genital shedding of HIV, and increased mortality... The outcomes of supplementation with single nutrients (vitamin E, selenium, zinc, and iron) are not yet conclusive.
Why this rating
The paper notes that supplementation outcomes are not yet conclusive and vary widely.
Source
Role of Nutrition in HIV Infection: Review of Evidence for more Effective Programming in Resource-Limited Settings
Saskia de Pee et al. · Food and Nutrition Bulletin · 2010
DOI 10.1177/15648265100314s403
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- HIV infection causes a state of malnutrition characterized by weight loss, micronutrient deficiencies, and altered metabolism, which accelerates disease progression and increases mortality risk independently of CD4 count.Good
- Antiretroviral therapy (ART) improves BMI and helps regain muscle mass, but weight loss can still occur in a significant proportion of patients on ART, necessitating concurrent nutritional interventions.Good
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