Research
Mixed
Multi-omics approaches (proteomics, transcriptomics) are necessary to accurately measure and understand the complexity of inflammaging, as single biomarkers like IL-6 or TNF-α are insufficient.
Current single-marker tests for inflammation are limited. Multi-omics approaches offer a more comprehensive view of inflammaging, which may lead to better diagnostics and targeted therapies in the future.
StrongSupportsHIGH confidence
Aging researchers now recognize that measuring a few cytokines in circulation fails to capture the complexity and potential ramifications of inflammaging.
Why this rating
Well-supported by the paper's discussion of current technological limitations and the need for multi-omics.
Source
Connecting aging biology and inflammation in the omics era
Keenan A. Walker et al. · Journal of Clinical Investigation · 2022
DOI 10.1172/jci158448
narrative_reviewCited 176×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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