Hormonal
Ad libitum diets with a low glycemic index (LGI) significantly reduce high-sensitivity C-reactive protein (hsCRP) levels beyond the reduction achieved by weight loss alone, independent of protein content.
If you are trying to lower inflammation markers like CRP after losing weight, prioritize foods with a low glycemic index (like legumes, whole grains, and non-starchy vegetables) over high-glycemic foods (like white bread and sugary snacks). This dietary choice provides an additional anti-inflammatory benefit beyond just maintaining your weight loss.
During the 26-week weight maintenance period in the intention-to-treat analysis, the further decrease of high-sensitivity C-reactive protein blood levels was −0.46 mg/L greater (95% confidence interval, −0.79 to −0.13) in the groups assigned to low-glycemic-index diets than in those on high-glycemic-index diets (P<0.001).
Why this rating
Large-scale (n=773 randomized), randomized controlled trial (RCT) with intention-to-treat analysis.
Source
Effects of Weight Loss and Long-Term Weight Maintenance With Diets Varying in Protein and Glycemic Index on Cardiovascular Risk Factors
Özlem Gögebakan et al. · Circulation · 2011
DOI 10.1161/circulationaha.111.033274
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