Micronutrients & recovery
A proprietary supplement containing 400 mg riboflavin, 600 mg magnesium, and 150 mg coenzyme Q10 taken daily for 3 months significantly reduces migraine pain intensity and disease burden compared to placebo, though it may not significantly reduce the total number of migraine days in underpowered trials.
If you suffer from frequent migraines and want to avoid prescription preventatives, try a supplement containing 400mg riboflavin, 600mg magnesium, and 150mg CoQ10 daily for at least 3 months. Expect a reduction in pain severity and overall disease burden, even if the number of migraine days doesn't drop drastically. Be aware that your urine may turn bright yellow (harmless) and you might experience mild digestive issues due to the magnesium.
The intensity of migraine pain was significantly reduced in the supplement group compared to placebo (p = 0.03). The sum score of the HIT-6 questionnaire was reduced by 4.8 points... compared to 2 points in the placebo-group (p = 0.01).
Why this rating
Randomized, double-blind, placebo-controlled trial with validated endpoints, though the primary endpoint failed to reach significance likely due to sample size.
Source
Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
on behalf of the Migravent® Study Group et al. · The Journal of Headache and Pain · 2015
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