Micronutrients & recovery
Melatonin acts as a potent antioxidant by scavenging reactive oxygen and nitrogen species, protecting against oxidative stress, and enhancing mitochondrial efficiency, independent of receptor binding.
Melatonin's role as an antioxidant helps protect cells from damage caused by stress and metabolism. This function supports overall cellular health and may be particularly relevant for brain health and aging, as melatonin protects against mitochondrial dysfunction associated with neurodegenerative diseases.
Melatonin is a highly effective ROS eliminator and exhibits numerous protective actions against oxidative stress, and is even reported to be 10× more powerful than vitamin E in scavenging ROS/RNS [116].
Why this rating
The paper cites multiple references ([116], [117], [118]) and describes a well-established cascade mechanism.
Source
Melatonin in Medicinal and Food Plants: Occurrence, Bioavailability, and Health Potential for Humans
Bahare Salehi et al. · Cells · 2019
DOI 10.3390/cells8070681
More from this paper
- Melatonin regulates circadian rhythms and sleep-wake cycles by acting on the suprachiasmatic nucleus (SCN) and pineal gland, with secretion peaking at night.Strong
- Dietary intake of melatonin-rich plant foods (particularly seeds and fruits) increases serum melatonin levels and urinary 6-sulfatoxymelatonin concentrations in humans, contributing to endogenous modulation.Moderate
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