Hormonal
The association between elevated BCAAs and insulin resistance is significantly modified by race, gender, and genetic variants affecting BCAA catabolism.
Your risk from high BCAAs depends on who you are. South Asians and Caucasians/Hispanics show a stronger link between high BCAAs and diabetes risk than African Americans. Men generally show a stronger correlation between BCAAs and insulin resistance than women. If you belong to these higher-risk groups, monitoring metabolic health is crucial.
Factors influencing BCAA level can be divided into four parts: race, gender, dietary patterns, and gene variants.
Why this rating
Consistent findings across multiple large cohort studies stratified by demographics.
Source
The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review
Xue Zhao et al. · Journal of Diabetes Research · 2016
DOI 10.1155/2016/2794591
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