Macro partitioning
Dietary interventions that restrict specific macronutrients (particularly protein and amino acids) or utilize time-restricted feeding can extend healthspan and lifespan without requiring overall caloric restriction.
You can improve your metabolic health and potentially extend lifespan without eating less food by changing WHAT and WHEN you eat. Focus on reducing protein and specific amino acids (like methionine) or restrict your eating to an 8-9 hour window each day. These strategies have been shown to prevent metabolic diseases even in mice eating unhealthy diets, suggesting they are powerful tools for human healthspan.
The restriction of specific macronutrients (or macronutrient restriction) without the restriction of calories is among the most promising interventions that have emerged to promote healthy aging in humans... Time-restricted feeding... prevented metabolic diseases in mice fed a high-fat diet... without lowering caloric intake.
Why this rating
Strong evidence in model organisms (flies, mice, rats); emerging evidence in humans (NHANES analysis).
Source
Dietary restriction with and without caloric restriction for healthy aging
Changhan Lee et al. · F1000Research · 2016
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →