Research

Hormonal

GLP-1 receptor agonists (e.g., semaglutide) and GLP-2 analogs (e.g., teduglutide) are FDA-approved interventions that treat obesity and short bowel syndrome by mimicking enteroendocrine cell hormone secretion.

If you have obesity or short bowel syndrome, talk to your doctor about GLP-1 based medications like semaglutide. These are FDA-approved treatments that mimic your gut's natural hormones to help with weight loss or nutrient absorption. They are not lifestyle fixes but medical interventions for specific conditions.

StrongSupportsVERY_HIGH confidence
One formulation of semaglutide, Wegovy, has recently been FDA-approved for treating obesity in adults and children over 12 years of age [140].
Roger Atanga et al. · International Journal of Molecular Sciences · 2023

Why this rating

The paper cites FDA approval and multiple clinical trials (Phase 2/3) for these specific drugs.

Source

Intestinal Enteroendocrine Cells: Present and Future Druggable Targets

Roger Atanga et al. · International Journal of Molecular Sciences · 2023

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