Research

Energy balance

The thermic effect of food (TEF) increases linearly with caloric intake and is independent of leanness or obesity when meals are normalized to fat-free mass.

If you are obese, your body does not necessarily process food calories differently than a lean person's body. The increase in energy expenditure after eating scales directly with how much you eat, regardless of your weight. Focus on the total amount of calories consumed rather than assuming your body is uniquely efficient at storing them.

GoodRefutesHIGH confidence
We conclude that the thermic effect of food increases linearly with caloric intake, and is independent of leanness and obesity.
David A. D’Alessio et al. · Journal of Clinical Investigation · 1988

Why this rating

Randomized controlled trial with rigorous indirect calorimetry and standardized meal protocols, though small sample size (n=10).

Source

Thermic effect of food in lean and obese men.

David A. D’Alessio et al. · Journal of Clinical Investigation · 1988

DOI 10.1172/jci113520

rct · n=10Cited 185×
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DOI resolved against Crossref · corpus check 2026-06-10

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