Hormonal
Sarcopenic obesity in elderly women is associated with significantly lower muscle strength and lean body mass, along with elevated pro-inflammatory markers (specifically IL-6) and glucose levels compared to nonsarcopenic obesity.
For elderly women, carrying excess fat combined with low muscle mass is worse for inflammation and strength than carrying excess fat alone. Screening for 'sarcopenic obesity' using appendicular lean mass relative to BMI can identify those at highest risk for disability, allowing for earlier, targeted strength and nutrition interventions.
The SO group presented a significantly greater BMI, fat (%), glucose, and a marginal trend toward significance for uric acid, and IL-6... In addition, the SO group displayed lower values for muscle strength and lean body mass.
Why this rating
Cross-sectional design limits causality; sample size is small (N=64); however, measurements are precise (DXA, enzymatic assays).
Source
The impact of sarcopenic obesity on inflammation, lean body mass, and muscle strength in elderly women
Dahan da Cunha Nascimento et al. · International Journal of General Medicine · 2018
DOI 10.2147/ijgm.s187285
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