Research
Mixed
OSH administration expands Akkermansia muciniphila abundance in the gut microbiota, which is associated with improved metabolic health.
This study shows that OSH can increase the levels of Akkermansia muciniphila, a bacterium linked to better metabolic health, in mice. This is a promising area of research, but it is not yet a proven strategy for humans.
ModerateSupportsMEDIUM confidence
OSH treatment confers protection from increased gut permeability... fostering Akkermansia muciniphila expansion.
Why this rating
Study is in mice, not humans.
Source
Biomimetic superabsorbent hydrogel acts as a gut protective dynamic exoskeleton improving metabolic parameters and expanding A. muciniphila
Alessandra Silvestri et al. · Cell Reports Medicine · 2023
DOI 10.1016/j.xcrm.2023.101235
mechanism_onlyCited 19×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Oral superabsorbent hydrogel (OSH) administration prevents diet-induced obesity and metabolic syndrome in mice by preserving gut barrier integrity and expanding Akkermansia muciniphila.Moderate
- OSH administration improves metabolic parameters, including glucose tolerance and insulin sensitivity, by increasing GLP-1 levels and protecting the intestinal barrier.Moderate
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