Research

Energy balance

A 12-month Mediterranean diet intervention in firefighters leads to modest but significant improvements in specific cardiometabolic markers, specifically body fat percentage and LDL cholesterol, at 6 months, though these effects may not persist or reach significance after multiple comparison corrections.

While the diet improves adherence, expect modest changes in body fat and LDL cholesterol, particularly in the first 6 months. Do not expect dramatic shifts in these specific markers, and be aware that statistical significance may be lost when accounting for multiple health metrics.

ModerateQualifiesMEDIUM confidence
Among secondary end points, the Mediterranean nutrition intervention group experienced a significantly greater decline in body fat percentage by 0.79 absolute percentage points... and LDL cholesterol by −6.92 mg/dL... at 6 months compared with controls... Correction for multiple comparisons resulted in a loss of statistical significance.
María Soledad Hershey et al. · JAMA Network Open · 2023

Why this rating

Statistical significance was lost after correction for multiple comparisons, reducing confidence in the robustness of these specific secondary findings.

Source

Effect of a Nutrition Intervention on Mediterranean Diet Adherence Among Firefighters

María Soledad Hershey et al. · JAMA Network Open · 2023

DOI 10.1001/jamanetworkopen.2023.29147

rct · n=485Cited 16×
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DOI resolved against Crossref · corpus check 2026-06-10

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