Research
Energy balance
Weight reduction interventions, including lifestyle changes and ACE inhibition, reduce glomerular hyperfiltration and proteinuria in obese patients with CKD.
If you are overweight and have diabetes, losing weight through diet and exercise can cut your risk of developing kidney disease by 30%. This benefit comes from reducing the strain on your kidneys, not just from better blood sugar control.
GoodSupportsHIGH confidence
In a recent meta-analysis collating experimental studies in obese CKD patients, interventions aimed at reducing body weight showed coherent reductions in blood pressure, glomerular hyper-filtration and proteinuria.
Why this rating
Supported by meta-analysis of experimental studies and post-hoc analysis of the REIN study.
Source
Obesity and Kidney Disease: Hidden Consequences of the Epidemic
Csaba P. Kövesdy et al. · Future Science OA · 2017
DOI 10.4155/fsoa-2016-0081
narrative_reviewCited 14×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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