Research

Mixed

Bariatric surgery (specifically sleeve gastrectomy and Roux-en-Y gastric bypass) achieves sustained weight loss and high rates of type 2 diabetes remission, while also significantly improving or resolving obstructive sleep apnea and metabolic dysfunction-associated steatotic liver disease (MASLD).

If you have severe obesity with diabetes or sleep apnea, bariatric surgery (sleeve or bypass) is the most effective current treatment for reversing these conditions. It offers the best chance for diabetes remission and resolving sleep apnea, though you must be monitored for potential liver issues if you lose weight too quickly.

GoodSupportsHIGH confidence
Bariatric surgery has been established as a highly effective option for patients with obesity to achieve sustained weight loss... There is clear evidence that bariatric surgery achieves meaningful remission rates of T2DM... Dramatic and sustainable weight loss, as seen in these surgeries, does see remarkable improvement and, in some cases, even the resolution of OSA... several studies have also shown improvement in MASLD both after SG and RYGB.
Christina Gu et al. · Journal of Clinical Medicine · 2024

Why this rating

Supported by multiple meta-analyses, RCTs (SM-BOSS, SOS), and large-scale registry studies.

Source

Potential Therapeutic Targets in Obesity, Sleep Apnea, Diabetes, and Fatty Liver Disease

Christina Gu et al. · Journal of Clinical Medicine · 2024

narrative_reviewCited 11×
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