Macro partitioning
Isocalorically substituting 5% of total energy intake from Animal Protein with Plant Protein is associated with a statistically significant reduction in all-cause mortality risk.
To potentially lower your risk of all-cause mortality, focus on swapping the energy from Animal Protein for Plant Protein. Specifically, aim to replace 5% of your total daily energy from animal sources (meat, dairy, eggs) with plant sources (beans, lentils, nuts, seeds). This swap is associated with a lower risk of death, according to a large network meta-analysis of observational studies.
We found moderate certainty of evidence for an association with lower risk of all-cause mortality, when replacing 5% of energy from animal protein... with plant protein (HR: 0.87; 95% CI: 0.84, 0.91).
Why this rating
The certainty of evidence is rated as 'moderate' by the authors using the GRADE approach, downgraded due to risk of bias in observational studies.
Source
Association between substituting macronutrients and all-cause mortality: a network meta-analysis of prospective observational studies
Sabina Wallerer et al. · EClinicalMedicine · 2024
DOI 10.1016/j.eclinm.2024.102807
More from this paper
- Isocalorically substituting 5% of total energy intake from carbohydrates with polyunsaturated fatty acids (PUFA), specifically n-3 and n-6, or plant-based monounsaturated fatty acids (MUFA) is associated with a statistically significant reduction in all-cause mortality risk.Moderate
- Isocalorically substituting 5% of total energy intake from Saturated Fatty Acids (SFA) and Trans-Fatty Acids (TFA) with Polyunsaturated Fatty Acids (PUFA) or Plant-based Monounsaturated Fatty Acids (MUFA) is associated with a statistically significant reduction in all-cause mortality risk.Moderate
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →