Research
Mixed
Prediabetic patients with obesity require comprehensive management of metabolic complications and specific prevention strategies to avoid progression to overt diabetes.
If you have prediabetes and are overweight, you cannot ignore it. You must actively manage your metabolic health through lifestyle changes and medical guidance to prevent full-blown diabetes.
ModerateSupportsMEDIUM confidence
Obesity in Prediabetic Patients: Management of Metabolic Complications and Strategies for Prevention of Overt Diabetes
Why this rating
It is a review article, not a primary clinical trial, providing expert synthesis rather than new primary data.
Source
Obesity in Prediabetic Patients: Management of Metabolic Complications and Strategies for Prevention of Overt Diabetes
Marco Chianelli et al. · Endocrine Metabolic & Immune Disorders - Drug Targets · 2024
DOI 10.2174/0118715303282327240507184902
narrative_reviewCited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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