Energy balance
Successful long-term weight loss maintenance (≥5% loss sustained for ~4.5 years) significantly lowers serum total cholesterol compared to unsuccessful maintainers, but does not significantly improve triglycerides, LDL, HDL, fasting glucose, or HbA1c in the long term.
Maintaining significant weight loss (≥5%) for several years is associated with lower total cholesterol compared to regaining the weight. However, do not assume this will automatically fix your triglycerides, LDL, or blood sugar. Long-term maintenance alone may not be enough to normalize all cardiometabolic markers; ongoing monitoring and potentially other lifestyle or medical interventions are necessary for comprehensive heart health.
The adjusted serum total cholesterol (TC) concentration was significantly lower for SWLM (5.17 ± 0.99 mmol/L) compared to UWLM (5.59 ± 1.06 mmol/L)... Serum low-density lipoprotein (LDL), high-density lipoprotein (HDL), fasting blood glucose (FBG), and glycosylated haemoglobin (HbA1c) concentrations for SWLM versus UWLM did not differ significantly... Triglyceride (TG) concentration was significantly (P < 0.001) lower for SWLM... After adjusting for covariates, it was no longer significant.
Why this rating
Cross-sectional study of a specific commercial program cohort; results are observational and adjusted for covariates, but lack randomization of the intervention itself.
Source
Impact of Successful Weight Loss Maintenance on Serum Lipids and Glucose Concentrations of Previous Participants of a Weight Loss Programme in Accra, Ghana
Sandra Ayisi Addo et al. · Journal of Nutrition and Metabolism · 2019
DOI 10.1155/2019/4729040
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