Research
Adherence
Anti-obesity medications should be used as part of a multidisciplinary approach that includes lifestyle changes, behavioral management, and long-term follow-up, rather than as a standalone solution.
Medication is a tool, not a cure. It works best when combined with healthy eating, physical activity, and behavioral support. Your doctor will likely recommend a multidisciplinary approach to ensure long-term success.
WeakQualifiesHIGH confidence
The authors concluded that anti-obesity treatments should be individualized and multidisciplinary.
Why this rating
Consensus of experts with high-level evidence references.
Source
Consensus on pharmacological treatment of obesity in Latin America
Ana María Cappelletti et al. · Obesity Reviews · 2023
DOI 10.1111/obr.13683
clinical_guidelineCited 7×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Pharmacological treatment for obesity is indicated for adults with a BMI ≥30 kg/m², or ≥27 kg/m² with at least one comorbidity, when lifestyle changes are insufficient to achieve or maintain weight loss objectives.Weak
- Pharmacological therapy should be discontinued if there is a lack of therapeutic response, defined as less than 5% weight loss after 12 weeks of optimal dosing, or if the patient experiences intolerance.Weak
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- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
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