Research
Mixed
Intensive lifestyle intervention for weight loss in adults with type 2 diabetes does not significantly alter the prevalence of abnormal ankle-brachial index (ABI), but it does significantly reduce interartery systolic blood pressure differences.
For people with type 2 diabetes, losing weight through diet and exercise improves how blood pressure varies between different arteries, which may indicate better vascular health, even if the standard ABI test (used to diagnose peripheral artery disease) doesn't show a change. Stick to the weight loss program for overall cardiovascular benefits.
StrongQualifiesHIGH confidence
Four years of intensive behavioral weight loss intervention did not significantly alter prevalence of abnormal ABI, however, it did reduce differences in systolic blood pressures among arterial sites.
Why this rating
Large-scale randomized clinical trial (Look AHEAD) with 5018 participants and 4-year follow-up.
Source
Impact of weight loss on ankle‐brachial index and interartery blood pressures
Mark A. Espeland et al. · Obesity · 2013
rct · n=5145Cited 7×
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