Adherence
Engagement with a nutritionist is a significant independent predictor of achieving relevant weight loss (≥7% and ≥10%) in MASLD patients, even when controlling for baseline BMI and other comorbidities.
If you have MASLD, seeking help from a qualified nutritionist significantly increases your chances of losing enough weight to improve your liver health. The study shows that patients who worked with a nutritionist were nearly 4 times more likely to lose 10% or more of their body weight. Make this a priority in your care plan.
Nutritionist support remained a favorable intervention, with an OR of 2.04 (95% CI: 1.12–3.71) of losing at least 7% and 3.80 (95% CI: 1.85–7.80) of losing at least 10%.
Why this rating
Retrospective observational data; the support was self-selected by patients, which may introduce selection bias (more motivated patients seek support).
Source
Key Predictors of Relevant Weight Loss in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease
Nicola Pugliese et al. · United European Gastroenterology Journal · 2025
DOI 10.1002/ueg2.70055
More from this paper
- In patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), achieving a baseline Body Mass Index (BMI) of 30 kg/m² or higher is a significant independent predictor of achieving clinically relevant weight loss (≥7% of initial body weight) through lifestyle interventions.Good
- Utilization of Glucagon-like peptide-1 (GLP-1) receptor agonists for Type 2 Diabetes is a significant independent predictor of achieving relevant weight loss (≥7%) in MASLD patients, with odds ratios increasing for greater weight loss thresholds.Good
Related findings · Adherence
- Regular physical activity (at least 150 minutes/week of moderate-intensity) reduces all-cause and cardiovascular mortality by 20-30% and lowers the risk of type 2 diabetes by 25-35%.Strong
- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →