Research
Energy balance
Bariatric surgery may not provide long-term reductions in depressive symptoms for patients with obesity and depression, despite improving quality of life.
Bariatric surgery is effective for weight loss but may not resolve depression long-term. Ensure you have a mental health support plan before and after surgery.
ModerateQualifiesMEDIUM confidence
Patients with depression and obesity may not experience long-term reductions in depressive symptoms after bariatric surgery even when quality of life is improved [134].
Why this rating
Based on a single citation (Ref 134) in the review.
Source
Treating obesity in patients with depression: a narrative review and treatment recommendation
Pamela Kushner et al. · Postgraduate Medicine · 2025
DOI 10.1080/00325481.2025.2478812
narrative_reviewCited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Phenotype-guided pharmacotherapy using naltrexone/bupropion extended-release (NB-ER) is the preferred treatment for obesity patients with emotional hunger, as it addresses both weight and depression symptoms.Good
- GLP-1 receptor agonists (liraglutide, semaglutide, tirzepatide) are effective for weight loss in patients with obesity and may improve depression scores, with a low rate of adverse psychiatric events.Good
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →