Mixed
Endoscopic sleeve gastroplasty (ESG) demonstrates a high safety profile with a serious adverse event (SAE) rate of 1.8%, significantly lower than laparoscopic sleeve gastrectomy (LSG), making it a preferred option for patients prioritizing safety over maximum weight loss efficacy.
If you are struggling with obesity (BMI 30-40) and have tried diet and exercise without success, ESG offers a middle ground between non-surgical methods and invasive surgery. It involves stitching the stomach to create a sleeve, which restricts food intake. The main benefit is safety: serious complications occur in less than 2% of cases, which is lower than traditional laparoscopic surgery. Expect a hospital stay of 2-3 days and an average procedure time of 55 minutes. While you may not lose as much weight as with invasive surgery, the risk profile is significantly more favorable.
The presented results confirm the high safety of ESG in the treatment of obesity... ESG achieves lower complication rates when compared with LSG... Gastrointestinal bleeding... occurs less frequently in ESG (Yoon, 1.1% vs. 2.6%, p < 0.05)... While both ESG and LSG may lead to new-onset GERD, the risk is lower in the case of ESG compared to LSG (Fayad L, 1.9% vs. 14.5%, p < 0.05).
Why this rating
Single-center retrospective study with a single operator; lacks randomization and long-term follow-up data.
Source
Endoscopic sleeve gastroplasty safety profile – retrospective, single-center analysis of 222 consecutive patients including the learning curve period
Przemysław Kasprzyk et al. · Videosurgery and Other Miniinvasive Techniques · 2024
DOI 10.5114/wiitm.2024.139687
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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