Mixed
An obesity-centric management approach utilizing a weight management program combined with anti-obesity medication (AOM) produces superior weight loss compared to usual glucose-centric care in patients with obesity and type 2 diabetes, while maintaining noninferior glycemic control.
For patients with obesity and type 2 diabetes, adopting an obesity-centric approach that combines a structured weight management program with FDA-approved anti-obesity medications leads to significantly greater weight loss compared to standard glucose-focused care, without compromising blood sugar control. This strategy addresses the root cause of obesity, offering a more comprehensive management plan.
In this study involving adults with type 2 diabetes and obesity, an obesity-centric approach characterized by participation in a weight management program including adjunctive AOMs produced superior weight loss as compared to usual glucose-centric care at 1 year.
Why this rating
Randomized controlled trial, but terminated early with a small sample size (n=74) due to recruitment challenges and COVID-19.
Source
An Obesity-Centric Approach with and Without Anti-Obesity Medications Compared to the Usual-Care Approach to Management of Patients with Obesity and Type 2 Diabetes in an Employer Setting: A Pragmatic Randomized Controlled Trial (EMPOWER-T2D)
Kevin M. Pantalone et al. · Diabetes Therapy · 2024
DOI 10.1007/s13300-024-01563-0
Related findings · Mixed
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