Mixed
Personalized nutrition significantly reduces HbA1c levels compared to standard control diets in adults with type 2 diabetes or prediabetes, with a median mean difference of -0.925%.
For adults with type 2 diabetes or prediabetes, using personalized nutrition strategies that incorporate individual biological data (like gut microbiome or genetic markers) alongside clinical metrics can lead to greater reductions in HbA1c compared to standard dietary advice. While the evidence quality is currently low due to study variability, the approach shows promise for improving glycemic control.
Personalized nutrition significantly reduced HbA1c (median mean difference: –0.925%, p < 0.01, 4 studies)... Personalized nutrition shows promise in improving HbA1c... in adults with diabetes mellitus type 2 or prediabetes.
Why this rating
GRADE assessment indicates 'Low' certainty due to risk of bias and heterogeneity.
Source
Effectiveness of Personalized Nutrition on Management Diabetes Mellitus Type 2 and Prediabetes in Adults: A Systematic Review
Elisa Fauziyatul Munawaroh et al. · Diabetes Metabolic Syndrome and Obesity · 2025
DOI 10.2147/dmso.s528619
More from this paper
- Personalized nutrition improves postprandial glycemic response (PPGR) compared to control diets, with a median mean difference of -14.85 mg/dLxh.Moderate
- Personalized nutrition does not significantly reduce fasting blood glucose compared to control diets in adults with prediabetes or type 2 diabetes.Moderate
- Personalized nutrition significantly reduces carbohydrate intake compared to control diets, with a median mean difference of -10.8% of energy.Limited
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