Research
Mixed
Combining diet, exercise, and medication therapy significantly increases the odds of achieving moderate weight loss (≥6 kg but <10 kg) compared to combined diet and exercise therapy alone.
If you are obese and have tried diet and exercise without achieving significant loss (≥6kg), adding prescribed medication therapy significantly increases your odds of success compared to diet and exercise alone.
ModerateSupportsMEDIUM confidence
Weight loss ≥6 kg but <10 kg was significantly associated with combined diet, exercise, and medication therapy among individuals who tried to lose weight in the past year.
Why this rating
Cross-sectional observational study; establishes correlation but not causation.
Source
The Effects of Weight Control Behaviors among Korean Obese Adults
Li-Ly Kang et al. · Korean Journal of Family Medicine · 2018
DOI 10.4082/kjfm.17.0021
cross_sectional · n=9461Cited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Combining diet therapy (reduced food intake) and exercise therapy significantly increases the odds of achieving moderate weight loss (≥3 kg but <6 kg) compared to using either therapy alone or no therapy.Moderate
- Only the combination of diet, exercise, and medication therapy was significantly correlated with significant weight loss (≥10 kg) in this study population.Limited
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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