Research
Adherence
Pharmacological treatment of obesity is ineffective and potentially harmful if not combined with lifestyle changes (calorie restriction and increased energy expenditure), as evidenced by 'stop rules' that mandate discontinuation if <5% weight loss occurs within 12 weeks.
Obesity drugs are not magic. They require you to eat less and move more. If you don't see at least 5% weight loss in 3 months on the full dose, the drug isn't working for you, and you should stop and try something else. Always combine medication with lifestyle changes for the best results.
StrongConditionalMEDIUM confidence
Drug administration without calorie restriction and increased energy expenditure may result in less than 5% body weight loss after 12 weeks... If, after 12 weeks, there is less than 5% weight loss with full-dose therapy... the drug should be discontinued.
Why this rating
Based on clinical guidelines and trial protocols described in the review.
Source
Current pharmacological approaches in obesity treatment
Pelin TİRYAKİOĞLU et al. · DAHUDER Medical Journal · 2023
narrative_reviewCited 2×
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