Hormonal

Current clinical-metabolomic biomarkers (including BCAA and lipid profiles) cannot predict individual changes in insulin sensitivity following lifestyle interventions, despite their ability to correlate with baseline insulin levels.

Do not rely on current commercial metabolomic tests (like BCAA or lipid profiling) to predict whether you will lose weight or improve insulin sensitivity through exercise or diet. These tests may tell you your current risk level, but they cannot tell you if a specific intervention will work for you. Monitor actual physiological changes using high-sensitivity insulin assays if possible.