Research
Micronutrients & recovery
Probiotic supplementation, particularly Lactobacillus species, reduces oral inflammation and may improve cognitive function in Alzheimer's patients by modulating the gut-brain axis and reducing pro-inflammatory cytokines.
Consider probiotic supplementation, particularly those containing Lactobacillus, as a potential adjunct to support oral health and cognitive function. While not a cure, they may help reduce inflammation and support the gut-brain axis.
ModerateSupportsMEDIUM confidence
Probiotics may also reduce the onset of AD by stimulating the production of GABA... a recent randomized, double blind, controlled, clinical trial showed that consumption of a mixture of probiotics over a 12-week period had a positive effect on cognitive function in AD patients (Pistollato et al., 2016).
Why this rating
Based on a specific RCT (Pistollato et al., 2016) and mechanistic studies; more evidence needed for long-term prophylactic use.
Source
Exploring the Association between Alzheimer’s Disease, Oral Health, Microbial Endocrinology and Nutrition
A. K. Harding et al. · Frontiers in Aging Neuroscience · 2017
DOI 10.3389/fnagi.2017.00398
narrative_reviewCited 108×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Chronic periodontitis acts as a source of systemic inflammation and oral pathogens (e.g., P. gingivalis) that contribute to the development and progression of Alzheimer's disease via immune subversion and blood-brain barrier compromise.Moderate
- Dietary interventions, specifically those rich in omega-3 fatty acids, polyphenols, and micronutrients (Mediterranean style), reduce systemic inflammation and periodontal disease, thereby potentially lowering the risk of Alzheimer's disease.Moderate
- Ketogenic interventions, including Medium Chain Triglycerides (MCTs) and coconut oil, provide an alternative energy source for the brain by increasing ketone bodies, which may benefit individuals with Alzheimer's disease or insulin resistance.Moderate
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