Research
Micronutrients & recovery
Probiotic supplementation, particularly Lactobacillus species, reduces oral inflammation and may improve cognitive function in Alzheimer's patients by modulating the gut-brain axis and reducing pro-inflammatory cytokines.
Consider probiotic supplementation, particularly those containing Lactobacillus, as a potential adjunct to support oral health and cognitive function. While not a cure, they may help reduce inflammation and support the gut-brain axis.
ModerateSupportsMEDIUM confidence
Probiotics may also reduce the onset of AD by stimulating the production of GABA... a recent randomized, double blind, controlled, clinical trial showed that consumption of a mixture of probiotics over a 12-week period had a positive effect on cognitive function in AD patients (Pistollato et al., 2016).
Why this rating
Based on a specific RCT (Pistollato et al., 2016) and mechanistic studies; more evidence needed for long-term prophylactic use.
Source
Exploring the Association between Alzheimer’s Disease, Oral Health, Microbial Endocrinology and Nutrition
A. K. Harding et al. · Frontiers in Aging Neuroscience · 2017
narrative_reviewCited 108×
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