Mixed
In integrated primary care weight management, achieving clinically meaningful weight loss (≥5% initial body weight) is significantly associated with higher treatment visit frequency and the simultaneous prescription of two or more anti-obesity medications (AOMs).
To maximize your chances of losing at least 5% of your body weight, commit to attending your scheduled monthly appointments for the first six months and discuss with your doctor the potential benefit of using two anti-obesity medications simultaneously if one isn't working. Consistent engagement and combination therapy were key factors in successful weight loss trajectories in this study.
Membership in this group and the Early Maintainer's group was associated with attending more visits and being prescribed at least two medications at the same time.
Why this rating
Retrospective observational study with potential confounding variables and self-reported data, but large sample size and real-world setting.
Source
Patterns of Weight Change Trajectories and Treatment Response in an Integrated Adult Primary Care Weight Management Practice
Anita Ganti et al. · Obesity Science & Practice · 2025
DOI 10.1002/osp4.70045
Related findings · Mixed
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