Hormonal
Replacing saturated animal fats with polyunsaturated vegetable oils (specifically linoleic acid-rich oils like safflower, canola, and hydrogenated oils) increases all-cause and cardiovascular mortality and accelerates atherosclerosis without lowering LDL-cholesterol in the long term.
Current mainstream guidelines recommending the substitution of animal fats with vegetable oils (high in linoleic acid) may be increasing health risks. The authors suggest restricting toxic vegetable oils (canola, hydrogenated oils) and increasing cholesterol and animal fat intake to non-obese levels, based on evidence that high cholesterol correlates with longevity and vegetable oils may accelerate disease via inflammatory and endocrine mechanisms.
In the Helsinki Businessmen Study [5], which involved longer-term dietary intervention... The CHD and all-cause mortality rates were found to be higher in the intervention group... No difference was noted in cholesterol levels at 10 years of intervention.
Why this rating
Relies heavily on re-analysis of older trials, animal models, and observational data; contradicts major consensus guidelines.
Source
Lipid Nutrition Guidelines
Harumi Okuyama et al. · 2021
DOI 10.3390/books978-3-03943-946-1
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