Research
Mixed
Both Low-Carbohydrate and Low-Fat diets can cause negative side effects, including gastrointestinal issues, fatigue, and in the case of LCD, potential risks like ketosis and kidney failure.
Be prepared for side effects when starting either diet. LCD may cause ketosis, fatigue, or kidney stress, while LFD may cause constipation and fatigue. Monitor your health and consult a physician, especially if you have pre-existing conditions.
ModerateQualifiesMEDIUM confidence
Negative effects were found from the LCD and LFD interventions such as constipation, fatigue, polyuria, nausea, vomiting, changes in appetite, and headaches. Kidney failure, ketosis, and premature coronary artery also occurred in the group that was given with LCD intervention.
Why this rating
Based on literature review citing various studies, side effects are reported but severity varies.
Source
The Effectiveness of Low-Carb Diet vs Low-Fat Diet on Body Composition in People with Obesity: A Literature Review
Tutut Rizki Indriyani et al. · Amerta Nutrition · 2024
DOI 10.20473/amnt.v8i1.2024.139-150
narrative_reviewCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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