Energy balance
Higher daily plain water intake is associated with a significantly lower risk of all-cause, cerebrovascular, and cancer mortality in patients with NAFLD or MASLD, with a non-linear dose-response relationship.
If you have fatty liver disease (NAFLD/MASLD), aim to increase your daily plain water intake. The study suggests that consuming around 2.8 liters (approx. 95 oz) of plain water per day is associated with a significantly lower risk of death from all causes, heart issues, and cancer compared to drinking less than 0.15 liters. If you currently drink sugary or artificial beverages, try replacing them with plain water; even small swaps (100mL) can reduce mortality risk. Always consult your doctor before making major changes, especially if you have fluid restrictions.
The multivariate Cox regression analyses revealed a significant association between higher plain water intake and lower all-cause mortality, cerebrovascular diseases mortality, and cancer mortality in both NAFLD or MASLD patients. Dose-response analyses revealed a non-linear trend between plain water intake and mortality among NAFLD/MASLD patients.
Why this rating
Observational cohort study (NHANES) with large sample size and long follow-up, but subject to residual confounding despite adjustments.
Source
Association of plain water intake with risk of all-cause and cause-specific mortality in individuals with non-alcoholic fatty liver disease or metabolic dysfunction-associated steatotic liver disease
Na Zhao et al. · Frontiers in Nutrition · 2024
DOI 10.3389/fnut.2024.1478194
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